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Percodan® (Oxycodone and Aspirin)

Combination of a pure opioid agonist Oxycodone hydrochloride and Aspirin.

  • Oxycodone Hydrochloride, USP……4.8355 mg*
  • Aspirin, USP…..325 mg
  • D&C Yellow 10
  • FD&C Yellow 6
  • Microcrystalline cellulose and corn starch

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Uses and Effects

Percodan is commonly prescribed for the relief of moderate to moderately severe pain. Oxycodone itself is an opioid narcotic analgesic and has a high potential for abuse. This medication should be taken as prescribed and never shared with others. The Oxycodone in Percodan® can cause physical and psychological dependence.  Because of the increasing numbers of patients addicted to oxycodone-containing drugs, the State of California, the California Medical Association and the House of Delegates, is recommending these medications return to its original level as triplicate as they were initially in 1949.

Although Percodan is not prescribed as often as drugs such as Percocet the drug has still potentially contributed to the opioid epidemic in the US.
One of the reasons for this epidemic was the changes in 1999 allowing doctors to prescribe narcotic painkillers a wider range of patients. New laws have made opioid drugs like Percodan very difficult to get, which led many people to seek illicit alternatives, such as heroin.

Possible Drug Interactions With Percodan

We are unable to list all possible drug interactions. Have a list of all prescription drugs you currently take, as well as herbal supplements; share the list with your healthcare professional.

Always seek your doctor’s approval prior to starting, stopping or changing dosage of any medication. Let your healthcare professional know if you have a history of seizures, brain tumors or a head injury.

  • Acetazolamide
  • Cimetidine
  • Corticosteroids
  • Mercaptopurine
  • Methotrexate
  • Mifepristone
  • Naltrexone
  • Muscle relaxants
  • The risk of bleeding may increase if taken with blood thinners (dabigatran, enoxaparin, warfarin, and others) or anti-platelet drugs (clopidogrel)
  • Pain medications (butorphanol, nalbuphine, pentazocine)


Store your medication at room temperature. Keep it away from light, high temperatures and moisture.
**Use this medicine with caution and under the close supervision of your healthcare professional.

Contact us and learn more about the best treatment options available for you!

Percodan Addiction and Abuse

Side Effects Can Include:

  • Bloating
  • Constipation – chronic constipation due to stomach and intestine motility can have a severe effect on the bowels.
  • Upset stomach
  • Heart Burn
  • Dry mouth
  • Drowsiness
  • A headache
  • Constipation
  • Breathing difficulties – like other opioids, Percodan can also reduce pulmonary function which directly affects breathing. Oxygen deprivation can damage the brain function and other organ systems.


If you experience any life-threatening, signs of an allergic reaction, such as difficulty breathing, swelling of throat, lips, tongue or face, seek emergency medical help.

Aside from the harm caused by the oxycodone portion, there are additional consequences due to the aspirin in Percodan. Too much aspirin is known to cause gastrointestinal issues including ulcers or lesions. Additionally, long-term aspirin intake can damage how platelets aggregate or clot. This condition can lead to bleeding disorders, including stroke. The epidemic and harm of opioid drugs are to such an extent that presently, overdoses are killing more people in the US than car accidents.

Overcoming a Percodan addiction is a huge challenge, one that requires professional help. Many people who try to quit “cold turkey,” end up relapsing and continuing the drug abuse. Furthermore, without professional help, the risk of progressing to stronger and more dangerous drugs is much higher, and so as overdose risks.

Percodan Withdrawal symptoms may include:

  • Agitation and anxiety
  • Muscle aches and joint pain
  • Insomnia and restlessness
  • Watery eyes
  • A runny nose
  • Sweating
  • Continuous yawning
  • Severe abdominal cramps
  • Nausea
  • Diarrhea and many other uncomfortable and physically risky conditions.


If you or someone you care about is misusing Percodan, please, seek professional assistance immediately. Some of the signs addiction is present may include, obsessing with finding and taking opioid drugs, losing interest in the hobbies or activities that once brought you joy, declining performance at work or school, and indifference to people and responsibilities.

Percodan Addiction Treatment Options

First and foremost, you need to find an effective detoxification center; a detoxification center that can get you through the withdrawal symptoms, safely and successfully. A program that can tailor the treatment to your specific health and dependence needs. Remember, you should not try to change your needs based on the treatment centers ability. On the contrary, the treatment center needs to modify the detoxification protocol so that it will work for you.

An excellent treatment program provides a wide range of detoxification options. The center needs to offer drug detoxification that is closely monitored by an experienced staff of doctors, nurses, and counselors — one that with the ability to modify the protocol as unique needs present themselves.

Due to potentially fatal complications caused by withdrawal effects, such as vomiting and diarrhea (which can lead to dehydration), a medically supervised detoxification is always the safest and most successful option.

Neonatal Opioid Withdrawal Syndrome

If a pregnant woman was on prolonged Percodan treatment, the patient needs to be advised of the dangers of neonatal opioid withdrawal syndrome, which could be life-threatening if not treated.

Percodan Rapid Detox and Non-Anesthesia Medically-Assisted Opioid Detoxification

After 22 years as one of the most successful opioid detoxification centers in the world, we understand that opioid use disorder affects everyone differently and symptoms vary from person to person. Furthermore, co-occurring health disorders such as diabetes, anxiety and depression could significantly impact how a patient experience withdrawal symptoms. Medical supervision with a wide range of resources is critical for anyone detoxing from drugs, alcohol or a patient with peripheral health issues.
For this and many other reasons, we provide medical detoxification in an accredited hospital followed by an exclusive recovery center.

Waismann Method® exclusive location is in Southern California, where we receive patients from all over the world. Patients are always treated in their private room, for optimal privacy, comfort, and more importantly, individualized care. Furthermore, our Multi Board-Certified Medical Director, speaks with every potential patient, before scheduling. In this way, we can provide a clear understanding of treatment options, risks and benefits. Our goal is to provide people suffering from substance abuse, the most advanced, effective and humane treatment available.

For more information, please call 1-855-539-3787. We are here for you seven days a week!

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