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Nucynta (Tapentadol)

What Is Nucynta?

Nucynta is the brand name of the generic drug tapentadol. It is a mu-opioid receptor agonist prescribed to manage moderate to severe acute pain in adults. Like other opioid pain medication, tapentadol is commonly called a narcotic.

The extended-release form of the drug is Nucynta ER. It is used for around-the-clock opioid treatment to control pain when alternative treatment options are inadequate. Nucynta is sometimes also used for purposes not in the medication guide.

Nucynta ER and the generic form of tapentadol are opioid agonists and Schedule II controlled substances that can be abused like any other legal or illicit opiate drug.

Because of the risks of abuse and misuse even at recommended doses, Nucynta ER is approved only for use in patients for whom alternative non-opioid medications or short-acting opioid options proved intolerable or ineffective in providing sufficient management of pain.

Abuse usually occurs when drug use goes beyond what the doctor prescribed. Opioid abuse commonly happens when physical dependence and tolerance develop, meaning higher dosages of the drug are needed to achieve the same effect the patient experienced when they began taking it. Once a dependency develops, reducing or stopping the drug intake produces withdrawal symptoms.

Signs of Nucynta (tapentadol) abuse include:

  • Analgesia
  • Confusion
  • Constipation
  • Euphoria
  • Itching or flushed skin
  • Nausea and vomiting
  • Respiratory depression (shallow or slow breathing)
  • Sedation
  • Slurred speech
  • Small pupils

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Tapentadol Addiction

Tapentadol addiction occurs when opioid abuse becomes compulsive and often self-destructive. It is usually characterized by an uncontrollable drug-seeking behavior, despite harmful consequences and brain chemistry changes. Drug addiction affects parts of the brain involved in reward and motivation, learning, memory, and the ability to control behavior. These shifts in the brain can lead to dangerous behaviors.

Possible Negative Effects of Nucynta Addiction

Opioid addiction slowly overpowers the logical thinking of the person taking a drug such as tapentadol or Nucynta. Loved ones are amazed as they witness the person’s self-destructive actions. Effects caused by opiate addiction can range from intangible losses to measurable losses. Losses incurred can affect not just the users but also the people around them. As priorities become displaced by the opiate addiction, these losses can include but are not limited to:

  • Employment
  • Financial responsibilities
  • Inhibitions
  • Motivation
  • Romantic relationships
  • Self-control and self-discipline
  • Self-esteem and self-worth
  • Trust

If you suspect a Nucynta overdose is occurring, please call 911 and seek immediate emergency medical attention or call the Poison helpline at 1-800-222-1222. Tapentadol overdose can be fatal.

Signs of Nucynta overdose may include:

  • Blurred vision
  • Cold and clammy skin
  • Confusion
  • Extreme drowsiness
  • Fainting
  • Shallow breathing
  • Slow heartbeat
  • Vomiting
  • Weak pulse


Interactions with alcohol and other depressants, such as sedatives, hypnotics, tranquilizers, and other opioids, also can result in an overdose.

Withdrawal symptoms may occur when sudden discontinuation of Nucynta occurs. These symptoms can include:

  • Anxiety
  • Diarrhea
  • Hallucinations, in rare cases
  • Insomnia
  • Nausea
  • Piloerection (goosebumps)
  • Rigors
  • Sweating
  • Tremors
  • Upper respiratory symptoms

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Nucynta Detox and Addiction Treatment

Anesthesia-assisted and sedation-assisted rapid detox can help you overcome Nucynta (tapentadol) withdrawal. When an opioid detox is improperly managed, it can have severe emotional and physiological consequences. At the world-renowned Waismann Method® opioid treatment center, however, your detox from prescription opioids such as Nucynta will be carefully supervised by our quadruple board-certified medical director in a private room to maximize your comfort and success.

Waismann Method® currently offers sedation-assisted detoxification treatment in an accredited private hospital for patients who have been unable to stop opioid use due to the intense withdrawal symptoms they have experienced or fear they might encounter. Our medical detoxification treatments work to meet each patient’s medical, dependent, and personal requirements.

After the hospital’s detoxification phase, patients remain at our private recovery center, Domus Retreat, for additional assistance as they adjust to being opioid-free. Waismann Method® and Domus Retreat have combined top professionals and private, accredited facilities with the most exceptional amenities to ensure maximum comfort and safety during your stay with us.

Are you ready to end the cycle of prescription drug abuse? Call us for the Waismann Treatment™ today at 855-539-3787.

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