Like all other opioid narcotics, long-term use of ACTIQ can lead to tolerance. In order words, the medication does not produce the same effects as it initially did. Individuals commonly increase their doses or combine the medicine with other narcotics or alcohol to intensify the effects. Both of these actions continually increase the risks of drug toxicity, overdose, and even death.
Over time the body adapts to function under the influence and effects of the ACTIQ. In order words, it will require the drug to feel and continue to work “normally.” Dependence can occur in anyone taking the medication continuously, regardless of the reason. Furthermore, those who have become physically dependent will need to keep using some form of an opioid drug, to avoid extremely uncomfortable withdrawal symptoms.