Zydone ® is the combination of two drugs, Hydrocodone Bitartrate and acetaminophen. Hydrocodone Bitartrate belongs to a class of drugs called opioid analgesics.

Zydone ® is indicated for the relief of moderate to moderately severe pain. Dosage may need to be adjusted while taking Zydone. Never attempt to adjust this on your own, always consult with your physician first. Hydrocodone may be habit forming, so take this medication exactly as directed. Never take Zydone ® more frequently or in higher doses until consulting with your healthcare professional.

Zydone Uses

Zydone is the brand name for tablets made up of hydrocodone and acetaminophen. There are three strengths of the drug, all which have 400 mg of acetaminophen. The hydrocodone strengths are 5 mg, 7.5 mg and 10 mg. Hydrocodone is an opiate analgesic and cough suppressant. Acetaminophen (Tylenol) is a milder pain reliever and non-narcotic. Zydone is indicated for pain that is moderate to moderately severe.

The combination of the two main ingredients is marketed under various names, including Vicodin, Norco, Lortab and Lorcet. Hydrocodone attaches to the opioid receptors in the brain and spinal cord to block pain. Acetaminophen decreases the formation of prostaglandins and increases pain-relieving power. Hydrocodone can be habit-forming if not used as prescribed. It is derived from the opium plant and classified as a Schedule II controlled substance in the U.S., meaning it has the potential to be abused and cause dependence.

Zydone Warnings

Zydone is intended to be taken whole. Crushing, chewing or snorting opiate drugs can lead to severe side effects or overdose. As with other opiates, warnings from manufacturers say Zydone should not be taken more often or in larger doses than what is prescribed. Anyone who has more than three alcoholic drinks per day or cirrhosis of the liver should talk to a doctor before taking any medication with acetaminophen. An overdose of acetaminophen can cause serious liver damage. The maximum recommended amount of acetaminophen for an adult is 1,000 mg per dose and 4,000 mg in a day. Doctors recommend knowing the amount of acetaminophen in each medication you take. Zydone can impair motor skills, affecting reaction time, and can cause changes in mood and thought processes. Warnings on the prescription say care should be taken when driving or performing other tasks that require alertness.

Possible Side Effects Of Zydone

Constipation, upset stomach, nausea, dizziness and dry mouth are considered among the most commonly reported side effects. Less common, but more serious, side effects include allergic reaction, clammy skin, seizures, extreme weakness, unconsciousness, jaundice, bleeding, bruising, decreased appetite, hot flashes, rash, itching, swelling, hearing loss, decreased sex drive and muscle twitches. Because of the hydrocodone, Zydone can also depress the central nervous system. Other side effects, which may attract some recreational users, include extreme relaxation, euphoria and drowsiness.

Tolerance, Dependency, Withdrawal And Detox

When taken as directed, Zydone can be a useful tool in pain relief. Prolonged use of opiates can lead to tolerance and dependence. Tolerance occurs when the drug builds up in the system, requiring people to take more to achieve the same pain-relieving effects. A tell-tale sign of dependence is a strong craving for the drug. Once addicted, withdrawal symptoms can set in. They include muscle and bone pain, insomnia, restlessness, diarrhea, vomiting, other flu-like symptoms and involuntary leg movements. Overdosing on Zydone or other opiates can be fatal. Kicking a Zydone addiction can be difficult. Many users delay treatment because of a fear of withdrawal. Numerous treatment options are available for opiate dependence. They include hospital-based detoxification, rehabilitation, faith or therapy-based programs and rapid drug detox.


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